Cheap Flights from San Francisco International to Knoxville

Travellers and cabin class

Compare San Francisco International to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

Book the best Knoxville fare with no extra fees

Flight deals from San Francisco International to Knoxville

Looking for a cheap last-minute deal or the best return flight from San Francisco International to Knoxville? Find the lowest prices on one-way and return tickets right here.

Find the cheapest month to fly from San Francisco International to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Francisco International to Knoxville flights are currently cheapest in May.

San Francisco International to Knoxville: Alternative routes

Compare routes from San Francisco International to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

San Francisco to Knoxville: Flight information

The things to know before you go.
Cheapest flight found284 €
Cheapest month to flyAugust

Finding cheap flights from San Francisco International to Knoxville: Frequently asked questions

The best price we found for a return flight from San Francisco International to Knoxville is 284 €. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from San Francisco International to Knoxville. But we found flights with one or more stops from 284 €.
As of April 2025, there are no flights flying from San Francisco International to Knoxville.
The cheapest month to fly from San Francisco International to Knoxville is usually April 2025.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Francisco International Airport to Knoxville Airport on Friday, 8 August 2025.
No airlines currently offer direct flights between San Francisco International Airport and Knoxville Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta offers the cheapest flight tickets to Knoxville.

Travelling from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS): what you need to know

  • If you're flying during a bank holiday or other peak period, allow extra time. A good rule is two hours ahead of domestic flights and up to four hours before international departures. Queues at security and check-in will be longer.

  • We make it easy to book a flight with a stopover. To look at your options for flights from San Francisco International Airport to McGhee Tyson Airport, deselect 'Direct flights only.' Then, pick a flight offering a stop long enough to explore your chosen city. Some popular stopovers between SFO and TYS are:

    • Hartsfield-Jackson Atlanta International Airport

    • Dallas/Fort Worth International Airport

    • Harry Reid Airport (formerly McCarran Airport)

How to find the cheapest flights from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS)

  • The lowest price we've seen for a one-way ticket from San Francisco International Airport to McGhee Tyson Airport is 138 €. For a return flight on this route, the best price is 284 €. Depending on the availability when you book, these fares could change.

  • Don't leave everything to the last moment. You're more likely to get cheap tickets from SFO to TYS if you book early. Airlines often offer some amazing early bird rates.

  • If you're willing to be flexible with your travel plans, try using the 'Whole month' tool. It'll give you the lowest price across every month when looking for your ticket from San Francisco International Airport to McGhee Tyson Airport.

  • Create a Price Alert for cheap tickets from SFO to TYS. There's no need to check back in every day to see if fares have dropped. We'll notify you as soon as there's a change in price.

  • Use filters to find the ideal journey for you. To see the 'Best,' 'Cheapest' or 'Fastest' flights from San Francisco International Airport to McGhee Tyson Airport, use the 'Sort by' function. You can also filter results by arrival and departure times, airline, and number of stops.

Handy information about San Francisco International Airport (SFO)

Arriving at McGhee Tyson Airport (TYS)

Getting from McGhee Tyson Airport (TYS) to central Knoxville

  • McGhee Tyson Airport is approximately 23 kilometres from the centre of Knoxville. With your own car rental or if you take a cab, the drive is about 19 minutes.

When to fly to McGhee Tyson Airport (TYS)

  • The quietest month for a flight from San Francisco International Airport to McGhee Tyson Airport is February, while July is the busiest. Pick the best time to go to Knoxville based on whether you prefer a bustling atmosphere or a more laid-back vibe.

  • Lock in your flight from San Francisco International Airport to McGhee Tyson Airport for July if you want to go to Knoxville during its warmest month. You can expect temperatures of between 17ºC and 32ºC.

  • Look for cheap tickets from SFO to TYS in January if you like cooler conditions. Temperatures are at their lowest then, ranging between -6ºC and 11ºC on average.

More about Knoxville

Complete your Knoxville trip with hotels and a car rental

  • Comparing flights is not the only thing we're good at. After booking your cheap ticket to McGhee Tyson Airport, browse our car rental deals that'll give you the freedom and flexibility to travel around at your own pace. Next, have a look at our exclusive rates for hotels to find your perfect Knoxville stay.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.